MMP2 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-434	100 μg

Catalog No. 89-120-434 Supplier Abnova Corporation Supplier No. PAB18873

Description

Rabbit polyclonal antibody raised against partial recombinant MMP2.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: MMP2
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against partial recombinant MMP2.
• Dilution: ELISA (1:20000-1:80000) Western Blot (1:200-1:1000) Immunohistochemistry (1:100-1:500) The optimal working dilution should be determined by the end user.
• Formulation: In buffer containing 0.02% sodium azide
• Gene: MMP2
• Gene Alias: CLG4/CLG4A/MMP-II/MONA/TBE-1
• Gene Symbols: MMP2
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to amino acids 257-500 of human MMP2.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4313
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only