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MRE11A Rabbit anti-Hamster, Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89115757 Shop All Abnova Corporation Products
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89-115-757 50 μL
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Catalog No. 89-115-757 Supplier Abnova Corporation Supplier No. PAB12381
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Description

Rabbit polyclonal antibody raised against MRE11A.

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]

Specifications

Antigen MRE11A
Applications Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against MRE11A.
Dilution Immunofluorescence (1:200) Western Blot (1:5000) The optimal working dilution should be determined by the end user.
Formulation In antiserum
Gene MRE11A
Gene Alias ATLD/HNGS1/MRE11/MRE11B
Gene Symbols MRE11A
Host Species Rabbit
Immunogen Full length human MRE11A.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4361
Test Specificity This antibody is specific to human Mre11.
Target Species Hamster, Human, Mouse
Content And Storage Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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