MRE11A Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-695	100 μg

Catalog No. 89-120-695 Supplier Abnova Corporation Supplier No. PAB19168

Description

Rabbit polyclonal antibody rasied against synthetic peptide of MRE11A.

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]

Specifications

• Antigen: MRE11A
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody rasied against synthetic peptide of MRE11A.
• Dilution: Western blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: MRE11A
• Gene Accession No.: EAW66932
• Gene Alias: ATLD/HNGS1/MRE11/MRE11B
• Gene Symbols: MRE11A
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 14 amino acids near N-terminus of human MRE11A.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4361
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only