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MSH6 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115312 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-115-312 100 μL
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Catalog No. 89-115-312 Supplier Abnova Corporation Supplier No. PAB11708

Description

Rabbit polyclonal antibody raised against synthetic peptide of MSH6.

This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq

Specifications

Antigen MSH6
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of MSH6.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene MSH6
Gene Alias GTBP/HNPCC5/HSAP
Gene Symbols MSH6
Host Species Rabbit
Immunogen A synthetic peptide corresponding to internal region of human MSH6.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2956
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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