MilliporeSigma™ Rabbit anti-MTHFR, Polyclonal,

Catalog No.	Quantity
ABS1013MI	200 μL

Catalog No. ABS1013MI Supplier MilliporeSigma™ Supplier No. ABS1013

Description

Rabbit Polyclonal Antibody

Specifically detects MTHFR in Human, Mouse, Porcine samples, and it is validated for Western Blotting

Methylenetetrahydrofolate reductase or 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20; UniProt P42898) is encoded by the MTHFR gene (Gene ID 4524) in human. MTHFR catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, the predominant circulatory form of folate and carbon donor for the re-methylation of homocysteine to methionine. Defects in MTHFR cause plasma homocysteine elevation or hperhomocysteinaemia, a risk factor for cerebrovascular, peripheral vascular, and coronary heart disease. Multiple transcription start sites and alternative splicing in the MTHFR gene result in two enzyme isoforms.

Specifications

• Antigen: MTHFR
• Applications: Western Blot
• Classification: Polyclonal
• Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
• Gene Accession No.: P42898
• Gene Symbols: MTHFR
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to human MTHFR.
• Purification Method: Unpurified
• Quantity: 200 μL
• Regulatory Status: RUO
• Research Discipline: Signaling
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_005948
• Target Species: Human, Mouse, Pig
• Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
• Form: Serum

For Research Use Only