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MUSK Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89130977 Shop All Abnova Corporation Products
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400 μL
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89-130-977 400 μL
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Catalog No. 89-130-977 Supplier Abnova Corporation Supplier No. PAB3370
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Description

Rabbit polyclonal antibody raised against synthetic peptide of MUSK.

Intercellular communication is often mediated by receptors on the surface of one cell that recognize and are activated by specific protein ligands released by other cells. Members of one class of cell surface receptors, receptor tyrosine kinases (RTKs), are characterized by having a cytoplasmic domain containing intrinsic tyrosine kinase activity. This kinase activity is regulated by the binding of a cognate ligand to the extracellular portion of the receptor. DeChiara et al. (1996) [PubMed 8653786] noted that the RTKs, known to be expressed in cell type-specific fashions, play a role critical for the growth and differentiation of those cell types. For example, members of the neural-specific TRK family that recognize nerve growth factor are absolutely required for the survival and development of discrete neuronal subpopulations, and the receptor tyrosine kinases TIE1 (MIM 600222) and TIE2 (MIM 600221) play a critical role in the development of normal blood vessels.[supplied by OMIM

Specifications

Antigen MUSK
Applications Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of MUSK.
Dilution Flow Cytometry (1:10-50) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene MUSK
Gene Alias MGC126323/MGC126324
Gene Symbols MUSK
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MUSK.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4593
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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