MYBPC3, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-119-449	100 μg

Catalog No. 89-119-449 Supplier Abnova Corporation Supplier No. PAB17783

Description

Rabbit polyclonal antibody raised against synthetic peptide of MYBPC3.

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq

Specifications

• Antigen: MYBPC3
• Applications: ELISA, Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MYBPC3.
• Dilution: Immunohistochemistry (1:50-1:100) ELISA (1:10000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
• Gene: MYBPC3
• Gene Alias: CMH4/DKFZp779E1762/FHC/MYBP-C
• Gene Symbols: MYBPC3
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to internal of human MYBPC3.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4607
• Test Specificity: This antibody detects endogenous levels of total MYBPC3 protein.
• Target Species: Human, Mouse
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only