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MYC (phospho S62), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of MYC.

Manufacturer:  Abnova Corporation PAB25882

Catalog No. 89-127-513


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Description

Description

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq

Sequence: P-L-Sp-P-S
Specifications

Specifications

MYC
1 mg/mL
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MYC.
In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Liquid
MYC
Synthetic phosphopeptide corresponding to residues surrounding S62 of human MYC.
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
Human, Murine, Rat
Immunofluorescence
Unconjugated
Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.
MYC
bHLHe39|c-Myc
Rabbit
Affinity chromatography
RUO
Primary
4609
SDS
Documents
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