MYC (phospho S62), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MYC.
Manufacturer: Abnova Corporation PAB25882
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeqSequence: P-L-Sp-P-S
|Rabbit polyclonal antibody raised against synthetic phosphopeptide of MYC.|
|In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|Synthetic phosphopeptide corresponding to residues surrounding S62 of human MYC.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Human, Murine, Rat|
|Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.|
For Research Use Only