Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. ABT1340

MilliporeSigma™ Rabbit anti-Myosin-10/MYH10/Myosin IIB, Polyclonal,

Catalog No. ABT1340 Shop All MilliporeSigma Products
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
ABT1340 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. ABT1340 Supplier MilliporeSigma™ Supplier No. ABT1340
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Specifically detects Myosin-10/MYH10/Myosin IIB in Human, Mouse samples, and it is validated for Immunofluorescence

Myosin-10 (UniProt P35580; also known as Cellular myosin heavy chain, type B, Myosin heavy chain 10, Myosin heavy chain, non-muscle IIb, NMMHC-B, NMMHC II-b, NMMHC-IIB, Non-muscle myosin heavy chain B, Non-muscle myosin heavy chain IIb) is encoded by the MYH10 (also known as NMMHCB) gene (Gene ID 4628) in human. Nonmuscle myosin II plays an important role in cell migration and invasion. The myosin II holoenzyme consists of two myosin heavy chains (MHCs), two essential light chains, and two regulatory light chains. Three different nonmuscle MHC II proteins exist in mammals, IIA (MYH9), IIB (MYH10), and IIC (MYH14), with both unique and overlapping roles. One of the initial steps in cancer cell metastasis is thought to be the process of epithelial–mesenchymal transition (EMT). Myosin IIB expression and myosin IIA heavy chain phosphorylation are upregulated upon TGF-β–induced EMT in mammary epithelial cells, while inhibition of myosin IIB expression in post-EMT mesenchymal cells reduces transmigration and invasion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Myosin-10/MYH10/Myosin IIB
Applications Immunofluorescence
Classification Polyclonal
Formulation Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No. P35580
Gene Symbols MYH10; NMMHCB
Host Species Rabbit
Immunogen KLH-conjugated linear peptide corresponding to the C-terminal sequence of human myosin-10.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Cell Structure
Primary or Secondary Primary
Gene ID (Entrez) NP_005955
Target Species Human, Mouse
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
Show More Show Less

For Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.