NBN Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of NBN.

Manufacturer:  Abnova Corporation PAB25488

Catalog No. 89-127-104

Description

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq

Specifications

• Antigen: NBN
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of NBN.
• Formulation: In PBS (0.02% sodium azide)
• Format: Liquid
• Gene Symbols: NBN
• Immunogen: A synthetic peptide corresponding to N-terminus of human NBN.
• Quantity: 100 ug
• Storage Requirements: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Polyclonal
• Test Specificity: At least three alternatively spliced transcript isoforms of NIBRIN are known to exist.

• Applications: ELISA, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1-2 ug/mL) Immunohistochemistry (2.5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: NBN
• Gene Alias: AT-V1|AT-V2|ATV|FLJ10155|MGC87362|NBS|NBS1|P95
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4683
• Target Species: Human, Murine, Rat

For Research Use Only