NBN Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of NBN.

Supplier:  Abnova Corporation PAB25488

Catalog No. 89-127-104

Description

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq

Specifications

• Antigen: NBN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1-2 ug/mL) Immunohistochemistry (2.5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: NBN
• Gene Symbols: NBN
• Immunogen: A synthetic peptide corresponding to N-terminus of human NBN.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: At least three alternatively spliced transcript isoforms of NIBRIN are known to exist.
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic peptide of NBN.
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: AT-V1/AT-V2/ATV/FLJ10155/MGC87362/NBS/NBS1/P95
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 4683
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only