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Description
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | NEFH |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | neurofilament, heavy polypeptide |
| Formulation | In PBS (0.02% sodium azide) |
| Gene | NEFH |
| Gene Alias | NFH |
| Gene Symbols | NEFH |
| Host Species | Rabbit |
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