NF1 Rabbit anti-Bovine, Dog, Human, Mouse, Rat, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of NF1.
Manufacturer: Abnova Corporation PAB12636
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq
|Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) The optimal working dilution should be determined by the end user.|
|Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
|This antibody recognizes ~240 KDa of human NF1 without the phosphorylation site of Ser 2741. It does not cross react to phospho NF1.|
|Dot Blot, ELISA, Immunoprecipitation, Western Blot|
|Rabbit polyclonal antibody raised against synthetic peptide of NF1.|
|In TBS, pH 7.2 (BSA, 10% Proclin300)|
|A synthetic peptide corresponding to residues surrounding S2741 of human NF1.|
|Bovine, Canine, Human, Murine, Rat|
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