NFKB1 Rabbit anti-Human, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of NFKB1.
Supplier: Abnova Corporation PAB25934
This gene encodes a 105kDa protein which can undergo cotranslational processing by the 26S proteasome to produce a 50kDa protein. The 105kDa protein is a Rel protein-specific transcription inhibitor and the 50kDa protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeqSequence: A-S-Sp-P-V
|Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to residues surrounding S893 of human NFKB1.|
|Immunohistochemistry (PFA fixed), Western Blot|
|Rabbit polyclonal antibody raised against synthetic peptide of NFKB1.|
|In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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