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NFKB1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115315 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-115-315 100 μL
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Catalog No. 89-115-315 Supplier Abnova Corporation Supplier No. PAB11710

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Rabbit polyclonal antibody raised against synthetic peptide of NFKB1.

This gene encodes a 105kDa protein which can undergo cotranslational processing by the 26S proteasome to produce a 50kDa protein. The 105kDa protein is a Rel protein-specific transcription inhibitor and the 50kDa protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen NFKB1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of NFKB1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene NFKB1
Gene Alias DKFZp686C01211/EBP-1/KBF1/MGC54151/NF-kappa-B/NFKB-p105/NFKB-p50/p105/p50
Gene Symbols NFKB1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus of human NFKB1.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4790
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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