MilliporeSigma™ Rabbit anti-NKp30/CD337, Polyclonal,

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABF127

Catalog No. ABF127MI

Description

Specifically detects NKp30/CD337 in Human samples, and it is validated for Immunohistochemistry, Western Blotting

Natural cytotoxicity triggering receptor 3 (UniProt O14931; also known as Activating NK-A1 receptor, Activating natural killer receptor p30, CD337, Lymphocyte antigen 117, Natural killer cell p30-related protein, NK-p30, NKp30) is encoded by the NCR3 (also known as 1C7, LY117, MALS) gene (Entrez Gene ID 259197) in human. NKp30/CD337 is a natural cytotoxicity receptor (NCR) that aids activated natural killer (NK) cells to mediate tumor cell lysis. NKp30 also helps eliminate immature DCs via BAG-6 (BCL2-associated athanogene 6 or Bat-3/Scythe) engagement, as well as by inducing TNF-alpha and IFN-gamma release from NK cells.

Specifications

• Antigen: NKp30/CD337
• Classification: Polyclonal
• Gene Accession No.: O14931
• Host Species: Rabbit
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human

• Applications: Immunohistochemistry, Western Blot
• Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: NCR3; 1C7; LY117
• Immunogen: KLH-conjugated linear peptide corresponding to the extracellular domain of human NKp30/CD337.
• Quantity: 200 μg
• Research Discipline: Inflammation and Immunology
• Gene ID (Entrez): NP_667341
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

For Research Use Only