NLRC4 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-114-080	50 μL

Catalog No. 89-114-080 Supplier Abnova Corporation Supplier No. PAB0258

Description

Rabbit polyclonal antibody raised against synthetic peptide of NLRC4.

In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM

Sequence: EEAPETYIPSRAVSLFFN

Specifications

• Antigen: NLRC4
• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of NLRC4.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In serum (0.05% sodium azide)
• Gene: NLRC4
• Gene Alias: CARD12/CLAN/CLAN1/CLANA/CLANB/CLANC/CLAND/CLR2.1/IPAF
• Gene Symbols: NLRC4
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to amino acids 637-654 of human NLRC4.
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 58484
• Target Species: Human, Mouse
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only