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Description
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined. [provided by RefSeq
Specifications
Specifications
| Antigen | NLRP12 |
| Applications | Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Immunoprecipitation |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of NLRP12. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In serum (0.05% sodium azide) |
| Gene | NLRP12 |
| Gene Alias | CLR19.3/FCAS2/NALP12/PAN6/PYPAF7/RNO/RNO2 |
| Gene Symbols | NLRP12 |
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