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NLRP6 Rabbit anti-Human, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of NLRP6.

Supplier:  Abnova Corporation PAB5471

Catalog No. 89-131-872


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Description

Description

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM

Specifications

Specifications

NLRP6
Polyclonal
Rabbit polyclonal antibody raised against synthetic peptide of NLRP6.
In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
CLR11.4/NALP6/PAN3/PYPAF5
Rabbit
100 μg
Primary
Human, Rat
Liquid
ELISA, Western Blot
Unconjugated
The optimal working dilution should be determined by the end user.
NLRP6
NLRP6
A synthetic peptide corresponding to C-terminus of human NLRP6.
RUO
171389
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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