NLRP6 Rabbit anti-Human, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of NLRP6.

Supplier:  Abnova Corporation PAB5471

Catalog No. 89-131-872

Description

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM

Specifications

• Antigen: NLRP6
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of NLRP6.
• Formulation: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
• Gene Alias: CLR11.4/NALP6/PAN3/PYPAF5
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Form: Liquid

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: NLRP6
• Gene Symbols: NLRP6
• Immunogen: A synthetic peptide corresponding to C-terminus of human NLRP6.
• Regulatory Status: RUO
• Gene ID (Entrez): 171389
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only