NLRP6 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody rasied against synthetic peptide of NLRP6.

Manufacturer:  Abnova Corporation PAB19304

Catalog No. 89-120-837

Description

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM

Specifications

• Antigen: NLRP6
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody rasied against synthetic peptide of NLRP6.
• Formulation: In PBS (0.02% sodium azide)
• Format: Liquid
• Gene Symbols: NLRP6
• Immunogen: A synthetic peptide corresponding to 16 amino acids near N-terminus of human NLRP6.
• Quantity: 100 ug
• Storage Requirements: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human

• Applications: ELISA, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1 ug/mL) Immunofluorescence (20 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: NLRP6
• Gene Alias: CLR11.4|NALP6|PAN3|PYPAF5
• Host Species: Rabbit
• Purification Method: Peptide affinity purification
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 171389

For Research Use Only