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NLRP6 Rabbit anti-Human, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody rasied against synthetic peptide of NLRP6.
Manufacturer: Abnova Corporation PAB19304
Description
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
Specifications
NLRP6 | |
Polyclonal | |
Unconjugated | |
Western Blot (1 ug/mL) Immunofluorescence (20 ug/mL) The optimal working dilution should be determined by the end user. | |
NLRP6 | |
NLRP6 | |
A synthetic peptide corresponding to 16 amino acids near N-terminus of human NLRP6. | |
100 μg | |
Primary | |
Human |
ELISA, Immunofluorescence, Western Blot | |
1 mg/mL | |
Rabbit polyclonal antibody rasied against synthetic peptide of NLRP6. | |
In PBS (0.02% sodium azide) | |
CLR11.4/NALP6/PAN3/PYPAF5 | |
Rabbit | |
Peptide affinity purification | |
RUO | |
171389 | |
Liquid |
Safety and Handling
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For Research Use Only