NLRP6 Rabbit anti-Human, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody rasied against synthetic peptide of NLRP6.
Manufacturer: Abnova Corporation PAB19304
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
|Rabbit polyclonal antibody rasied against synthetic peptide of NLRP6.|
|In PBS (0.02% sodium azide)|
|A synthetic peptide corresponding to 16 amino acids near N-terminus of human NLRP6.|
|Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|ELISA, Immunofluorescence, Western Blot|
|Western Blot (1 ug/mL) Immunofluorescence (20 ug/mL) The optimal working dilution should be determined by the end user.|
|Peptide affinity purification|
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