NOD2 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of NOD2.

Supplier:  Abnova Corporation PAB13103

Catalog No. 89-116-355

Description

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq

Specifications

• Antigen: NOD2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of NOD2.
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: ACUG/BLAU/CARD15/CD/CLR16.3/IBD1/NLRC2/NOD2B/PSORAS1
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: NOD2 has no cross-reaction with NOD1.
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunocytochemistry, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (2-4 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: NOD2
• Gene Symbols: NOD2
• Immunogen: A synthetic peptide corresponding to C-terminus 14 amino acids of human NOD2.
• Regulatory Status: RUO
• Gene ID (Entrez): 64127
• Target Species: Human
• Form: Liquid

For Research Use Only