NOTCH2 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-121-375	100 μg

Catalog No. 89-121-375 Supplier Abnova Corporation Supplier No. PAB19843

Description

Rabbit polyclonal antibody raised against synthetic peptide of NOTCH2.

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. [provided by RefSeq

Specifications

• Antigen: NOTCH2
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of NOTCH2.
• Dilution: ELISA (1:160000) Western Blot (1:500-1000) The optimal working dilution should be determined by the end user.
• Formulation: In serum (0.02% sodium azide)
• Gene: NOTCH2
• Gene Alias: AGS2/hN2
• Gene Symbols: NOTCH2
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to amino acids 1719-1733 of human NOTCH2.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4853
• Target Species: Human
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only