NRAS Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-128-949	100 μg

Catalog No. 89-128-949 Supplier Abnova Corporation Supplier No. PAB27439

Description

Rabbit polyclonal antibody raised against synthetic peptide of NRAS.

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). [provided by RefSeq

Specifications

• Antigen: NRAS
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of NRAS.
• Dilution: Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.02% sodium azide)
• Gene: NRAS
• Gene Alias: ALPS4/N-ras/NRAS1
• Gene Symbols: NRAS
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 15 amino acids at C-terminus of human NRAS.
• Purification Method: Peptide affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4893
• Test Specificity: NRAS antibody is predicted to not cross-react with H-RAS
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG

For Research Use Only