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NRG1 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89118984 Shop All Abnova Corporation Products
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89-118-984 100 μg
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Catalog No. 89-118-984 Supplier Abnova Corporation Supplier No. PAB17327
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Rabbit polyclonal antibody raised against synthetic peptide of NRG1.

The protein encoded by this gene was originally identified as a 44kDa glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq

Specifications

Antigen NRG1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of NRG1.
Dilution Western Blot (1:300-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:10000) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Gene NRG1
Gene Alias ARIA/GGF/GGF2/HGL/HRG/HRG1/HRGA/NDF/SMDF
Gene Symbols NRG1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to human NRG1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3084
Test Specificity This antibody detects endogenous levels of total NRG1 protein.
Target Species Human, Mouse
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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