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NRG1 Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™

Catalog No. 89129676 Shop All Abnova Corporation Products
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89-129-676 50 μg
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Catalog No. 89-129-676 Supplier Abnova Corporation Supplier No. PAB28169
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Description

Rabbit polyclonal antibody raised against synthetic peptide of NRG1.

The protein encoded by this gene was originally identified as a 44kDa glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq

Specifications

Antigen NRG1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of NRG1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/ml)
Formulation In PBS (0.09% sodium azide)
Gene NRG1
Gene Alias ARIA/GGF/GGF2/HGL/HRG/HRG1/HRGA/NDF/SMDF
Gene Symbols NRG1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 17 amino acids at internal region of human NRG1.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3084
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Human, Monkey
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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