NTRK1 (phospho Y757), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NTRK1.

Supplier:  Abnova Corporation PAB29221

Catalog No. 89-130-656

Description

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq

Specifications

• Antigen: NTRK1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human NTRK1.
• Formulation: In PBS, pH 7.4 (without Mg²⁺ and Ca²⁺), (50% glycerol, 0.02% sodium azide)
• Gene Alias: DKFZp781I14186/MTC/TRK/TRK1/TRKA/p140-TrkA
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 4914
• Target Species: Human, Mouse
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
• Gene: NTRK1
• Gene Symbols: NTRK1
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y757 of human NTRK1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This antibody detects endogenous levels of NTRK1 only when phosphorylated at tyrosine 757.
• Content And Storage: Store at -20°C.
  Avoid repeated freezing and thawing.

For Research Use Only