OGG1, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-115-586	100 μL

Catalog No. 89-115-586 Supplier Abnova Corporation Supplier No. PAB12085

Description

Rabbit polyclonal antibody raised against synthetic peptide of OGG1.

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq

Specifications

• Antigen: OGG1
• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of OGG1.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000) Immunohistochemistry (Frozen sections) (1:25-1:100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: OGG1
• Gene Alias: HMMH/HOGG1/MUTM/OGH1
• Gene Symbols: OGG1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to amino acids 1-100 of human OGG1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4968
• Test Specificity: This antibody is specific to human Ogg1.
• Target Species: Human, Primate, Rat
• Content And Storage: Store at 4°C. Do not freeze.
• Form: Liquid

For Research Use Only