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OPN4 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89126691 Shop All Abnova Corporation Products
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89-126-691 100 μL
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Catalog No. 89-126-691 Supplier Abnova Corporation Supplier No. PAB25013
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Rabbit polyclonal antibody raised against synthetic peptide of OPN4.

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Specifications

Antigen OPN4
Applications Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of OPN4.
Dilution Western Blot (1:500-1:1000) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.05% sodium azide)
Gene OPN4
Gene Alias MGC142118/MOP
Gene Symbols OPN4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to OPN4.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 94233
Test Specificity OPN4 polyclonal antibody detects endogenous levels of OPN4.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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