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Description
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Specifications
Specifications
| Antigen | OS9 |
| Applications | Immunofluorescence, Immunohistochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of OS9. |
| Dilution | Immunofluorescence (0.2-1 ug/mL) Immunohistochemistry (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:250) Western Blot (0.2-1 ug/mL) The optimal working dilution should be determined by the end user |
| Formulation | In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.01% sodium azide) |
| Gene | OS9 |
| Gene Symbols | OS9 |
| Host Species | Rabbit |
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