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Description
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq
Specifications
Specifications
| Antigen | OSBPL2 |
| Applications | Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against recombinant OSBPL2. |
| Dilution | Immunohistochemistry (1:200-1:500) Western Blot (1:100-1:250) Immunofluorescence (1-4 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.2, (40% glycerol, 0.02% sodium azide) |
| Gene | OSBPL2 |
| Gene Alias | FLJ20223/KIAA0772/MGC4307/MGC8342/ORP-2/ORP2 |
| Gene Symbols | OSBPL2 |
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