P2RX7, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-129-344	50 μg

Catalog No. 89-129-344 Supplier Abnova Corporation Supplier No. PAB27822

Description

Rabbit polyclonal antibody raised against synthetic peptide of P2RX7.

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq

Specifications

• Antigen: P2RX7
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of P2RX7.
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10-20 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: P2RX7
• Gene Alias: MGC20089/P2X7
• Gene Symbols: P2RX7
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to 16 amino acid at internal region of human P2RX7.
• Purification Method: Immunoaffinity chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5027
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DDX59 (56%).
• Target Species: Human, Monkey
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only