MilliporeSigma™ Rabbit anti-p47-phox, Polyclonal,

Catalog No.	Quantity
ABN1480MI	100 μg

Catalog No. ABN1480MI Supplier MilliporeSigma™ Supplier No. ABN1480

Description

Rabbit Polyclonal Antibody

Specifically detects p47-phox in Human, Mouse samples, and it is validated for Immunohistochemistry, Western Blotting

Neutrophil cytosol factor 1 (UniProt Q09014), also known as 47kDa neutrophil oxidase factor, NADPH oxidase subunit, Ncf-1, NCF-47K, Neutrophil NADPH oxidase factor 1, p47-phox, p47phox) is encoded by the Ncf1 gene in murine species. Activation of NADPH-oxidase dependent superoxide generation requires the participation of several cytosolic factors, including p47-phox, p67-phox, p40-phox and Rac. In the resting cell, p47phox, p67phox, and p40phox form a large molecular weight cytosolic complex. Activation of the NADPH oxidase is initiated by the assembly of p47phox, p67phox, and Rac with cytochrome b558 in a 1:1:1:1 complex in the plasma membrane.

Specifications

• Antigen: p47-phox
• Applications: Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: Q09014
• Gene Symbols: Ncf1
• Host Species: Rabbit
• Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of mouse p47-phox.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Neuroscience
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_001272966
• Target Species: Human, Mouse
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

For Research Use Only