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PAK3, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89124699 Shop All Abnova Corporation Products
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400 μL
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89-124-699 400 μL
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Catalog No. 89-124-699 Supplier Abnova Corporation Supplier No. PAB2300
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Description

Rabbit polyclonal antibody raised against synthetic peptide of PAK3.

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of nonsyndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq

Specifications

Antigen PAK3
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PAK3.
Dilution Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PAK3
Gene Alias CDKN1A/MRX30/MRX47/OPHN3/PAK3beta/bPAK/hPAK3
Gene Symbols PAK3
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to internal region of human PAK3.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5063
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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