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PAK4 (phospho S474), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89115976 Shop All Abnova Corporation Products
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100 μg
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89-115-976 100 μg
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Catalog No. 89-115-976 Supplier Abnova Corporation Supplier No. PAB12642
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of PAK4.

PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq

Sequence: RKSLV

Specifications

Antigen PAK4
Applications ELISA, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of PAK4.
Dilution Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In TBS, pH 7.2 (BSA, 10% Proclin300)
Gene PAK4
Gene Symbols PAK4
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding S474 of human PAK4.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10298
Test Specificity This antibody recognizes PAK4 at a phosphorylation site of Serine 474 (∼68KDa), or serine 602 of PAK5 (∼90KDa) or Serine 560 of PAK6 (∼80 KDa). It does not cross react to other PAK1, PAK2 or PAK3.
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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