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PAK6 Rabbit anti-Bovine, Chicken, Dog, Horse, Human, Monkey, Mouse, Rabbit, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89118289 Shop All Abnova Corporation Products
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50 μg
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89-118-289 50 μg
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Catalog No. 89-118-289 Supplier Abnova Corporation Supplier No. PAB16417
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Description

Rabbit polyclonal antibody raised against synthetic peptide of PAK6.

This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

Specifications

Antigen PAK6
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PAK6.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PAK6
Gene Alias PAK5
Gene Symbols PAK6
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human PAK6.
Purification Method Immunoaffinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56924
Test Specificity N-terminal domain of human.
Target Species Bovine, Canine, Chicken, Equine, Human, Monkey, Mouse, Rabbit, Rat
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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