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PAK7 Rabbit anti-Dog, Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89119578 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-119-578 100 μg
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Catalog No. 89-119-578 Supplier Abnova Corporation Supplier No. PAB17958

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Rabbit polyclonal antibody raised against synthetic peptide of PAK7.

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq

Specifications

Antigen PAK7
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description p21 protein (Cdc42/Rac)-activated kinase 7
Formulation In PBS pH 7.2 (30% glycerol, 0.5% BSA, 0.01% thimerosal)
Gene PAK7
Gene Alias KIAA1264, MGC26232, PAK5
Gene Symbols PAK7
Host Species Rabbit
Immunogen A synthetic peptide corresponding to the residues surrounding amino acid 90 of human PAK7.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57144
Test Specificity This antibody recognizes ∽80kDa of Pak5/PAK7 from samples of human, mouse, rat and dog origins.
Target Species Canine, Human, Mouse, Rat
Content And Storage Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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