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PAK7 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89127195 Shop All Abnova Corporation Products
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50 μg
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89-127-195 50 μg
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Catalog No. 89-127-195 Supplier Abnova Corporation Supplier No. PAB25580
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Description

Rabbit polyclonal antibody raised against synthetic peptide of PAK7.

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq

Specifications

Antigen PAK7
Applications ELISA, Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PAK7.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PAK7
Gene Alias KIAA1264/MGC26232/PAK5
Gene Symbols PAK7
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 18 amino acids at internal region of human PAK7.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57144
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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