PANK2 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PANK2.

Supplier:  Abnova Corporation PAB2719

Catalog No. 89-128-842

Description

This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq

Specifications

• Antigen: PANK2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PANK2.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: C20orf48/FLJ17232/HARP/HSS/MGC15053/NBIA1/PKAN
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 80025
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: PANK2
• Gene Symbols: PANK2
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PANK2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only