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PARP1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115335 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-115-335 100 μL
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Catalog No. 89-115-335 Supplier Abnova Corporation Supplier No. PAB11729

Description

Rabbit polyclonal antibody raised against synthetic peptide of PARP1.

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq

Specifications

Antigen PARP1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PARP1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene PARP1
Gene Alias ADPRT/ADPRT1/PARP/PARP-1/PPOL/pADPRT-1
Gene Symbols PARP1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus of human PARP1.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 142
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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