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Description
PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
Specifications
Specifications
| Antigen | PAX2 |
| Applications | Immunofluorescence, Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.75-0.95 mg/mL |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of PAX2. |
| Dilution | Western Blot (1:500) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris-glycine buffer, pH 7.4 (stabilizing proteins, cryogenic stabilizers, glycerol, 0.02% sodium azide) |
| Gene | PAX2 |
| Gene Symbols | PAX2 |
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