Learn More
Description
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq
Specifications
Specifications
| Antigen | PCSK9 |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against full length recombinant PCSK9. |
| Dilution | Western Blot (0.5-1 ug/mL) Immunoprecipitation (1-2 ug/sample) The optimal working dilution should be determined by the end user. |
| Formulation | In 10mM phosphate buffer, 150mM NaCl, pH 7.5 (50% glycerol) |
| Gene | PCSK9 |
| Gene Alias | FH3/HCHOLA3/LDLCQ1/NARC-1/NARC1 |
| Gene Symbols | PCSK9 |
| Show More |
For Research Use Only
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.