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PDE11A Rabbit anti-Bovine, Chicken, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebra fish, Polyclonal Antibody, Abnova™
Shop All Abnova Corporation ProductsDescription
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Specifications
Specifications
| Antigen | PDE11A |
| Applications | Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of PDE11A. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | PDE11A |
| Gene Alias | FLJ23693/MGC133355/MGC133356/PPNAD2 |
| Gene Symbols | PDE11A |
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For Research Use Only
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