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PDE4B, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89115737 Shop All Abnova Corporation Products
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89-115-737 50 μL
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Catalog No. 89-115-737 Supplier Abnova Corporation Supplier No. PAB12353
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Description

Rabbit polyclonal antibody raised against PDE4B.

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq

Specifications

Antigen PDE4B
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against PDE4B.
Dilution Western Blot (1:20000) The optimal working dilution should be determined by the end user.
Formulation In serum
Gene PDE4B
Gene Alias DKFZp686F2182/DPDE4/MGC126529/PDE4B5/PDEIVB
Gene Symbols PDE4B
Host Species Rabbit
Immunogen C terminal region of human PDE4B.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5142
Test Specificity This antibody selectively detects proteins corresponding to members of the PDE4B sub-family.
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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