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PDE6A, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89118306 Shop All Abnova Corporation Products
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89-118-306 50 μg
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Catalog No. 89-118-306 Supplier Abnova Corporation Supplier No. PAB16433
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Description

Rabbit polyclonal antibody raised against synthetic peptide of PDE6A.

This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq

Specifications

Antigen PDE6A
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PDE6A.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PDE6A
Gene Alias CGPR-A/PDEA
Gene Symbols PDE6A
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human PDE6A.
Purification Method Immunoaffinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5145
Test Specificity N-terminal region of human.
Target Species Hamster, Human, Monkey, Mouse, Rat
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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