PDE6A, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of PDE6A.

Manufacturer:  Abnova Corporation PAB16433

Catalog No. 89-118-306

Description

This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq

Specifications

• Antigen: PDE6A
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PDE6A.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: CGPR-A/PDEA
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 5145
• Target Species: Hamster, Human, Monkey, Mouse, Rat

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: PDE6A
• Gene Symbols: PDE6A
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human PDE6A.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: N-terminal region of human.
• Form: Liquid

For Research Use Only