PDE8A Rabbit anti-Dog, Horse, Human, Mouse, Pig, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-118-297	50 μg

Catalog No. 89-118-297 Supplier Abnova Corporation Supplier No. PAB16424

Description

Rabbit polyclonal antibody raised against synthetic peptide of PDE8A.

Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (Hetman et al., MIM 2000). See MIM 171885.[supplied by OMIM

Specifications

• Antigen: PDE8A
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PDE8A.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: PDE8A
• Gene Alias: FLJ16150/HsT19550
• Gene Symbols: PDE8A
• Host Species: Rabbit
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human PDE8A.
• Purification Method: Immunoaffinity purification
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5151
• Test Specificity: Near N-terminus of human.
• Target Species: Canine, Equine, Human, Mouse, Pig, Rabbit
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only