PDE8A Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-336	400 μL

Catalog No. 89-120-336 Supplier Abnova Corporation Supplier No. PAB1878

Description

Rabbit polyclonal antibody raised against synthetic peptide of PDE8A.

Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (Hetman et al., MIM 2000). See MIM 171885.[supplied by OMIM

Specifications

• Antigen: PDE8A
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of PDE8A.
• Dilution: Western Blot (1:1000) Immunohistochemistry (1:50) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: PDE8A
• Gene Alias: FLJ16150/HsT19550
• Gene Symbols: PDE8A
• Host Species: Rabbit
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding L572 of human PDE8A (L572).
• Purification Method: Protein A purification
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5151
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only