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PDE8B Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™

Catalog No. 89118299 Shop All Abnova Corporation Products
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89-118-299 50 μg
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Catalog No. 89-118-299 Supplier Abnova Corporation Supplier No. PAB16426
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Description

Rabbit polyclonal antibody raised against synthetic peptide of PDE8B.

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the 5-prime,3-prime-cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been grouped into several families based on substrate affinities, inhibitor sensitivities, mode of regulation, and amino acid sequence homologies. The PDE8 family contains high-affinity cAMP-specific, IBMX (3-isobutyl-1-methyl-xanthine)-insensitive PDEs, such as PDE8B. All PDEs share a conserved C-terminal catalytic region and a variable N-terminal domain that presumably accounts for the distinctive regulatory properties unique to the individual families.[supplied by OMIM

Specifications

Antigen PDE8B
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PDE8B.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PDE8B
Gene Alias FLJ11212/PPNAD3
Gene Symbols PDE8B
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human PDE8B.
Purification Method Immunoaffinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8622
Test Specificity Internal domain of human.
Target Species Human, Monkey
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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