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PDGFRB Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115339 Shop All Abnova Corporation Products
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89-115-339 100 μL
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Catalog No. 89-115-339 Supplier Abnova Corporation Supplier No. PAB11732

Description

Rabbit polyclonal antibody raised against synthetic peptide of PDGFRB.

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq

Specifications

Antigen PDGFRB
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PDGFRB.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene PDGFRB
Gene Alias CD140B/JTK12/PDGF-R-beta/PDGFR/PDGFR1
Gene Symbols PDGFRB
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus of human PDGFRB.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5159
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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For Research Use Only

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