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PDGFRB Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89130979 Shop All Abnova Corporation Products
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400 μL
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89-130-979 400 μL
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Catalog No. 89-130-979 Supplier Abnova Corporation Supplier No. PAB3375
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Rabbit polyclonal antibody raised against synthetic peptide of PDGFRB.

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq

Specifications

Antigen PDGFRB
Applications ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of PDGFRB.
Dilution Flow Cytometry (1:10-50) Immunofluorescence (1:10-50) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-50) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene PDGFRB
Gene Alias CD140B/JTK12/PDGF-R-beta/PDGFR/PDGFR1
Gene Symbols PDGFRB
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PDGFRB.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5159
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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