PDHA1, Rabbit, DyLight 649, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-117-569	50 μL

Catalog No. 89-117-569 Supplier Abnova Corporation Supplier No. PAB15339

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of PDHA1.

The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM

Specifications

• Antigen: PDHA1
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: DyLight 649
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of PDHA1.
• Dilution: Western Blot (1:2500-1:5000) The optimal working dilution should be determined by the end user.
• Formulation: In 50mM sodium borate
• Gene: PDHA1
• Gene Alias: PDHA/PDHCE1A/PHE1A
• Gene Symbols: PDHA1
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S293 human PDHA1.
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5160
• Test Specificity: This is specific to the phosphorylated Serine 293 form of the PDHE1 alpha protein. This antibody is useful for Western blot, where a band is seen ∼43 KDa.
• Target Species: Human
• Content And Storage: Store at 4°C. Do not freeze.
• Form: Liquid

For Research Use Only