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PEX5, Rabbit, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against recombinant PEX5.
Supplier: Abnova Corporation PAB23410
Description
The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Sequence: DAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLASpecifications
PEX5 | |
Polyclonal | |
Rabbit polyclonal antibody raised against recombinant PEX5. | |
In PBS, pH 7.5 (40% glycerol, 0.02% sodium azide) | |
FLJ50634/FLJ50721/FLJ51948/PTS1-BP/PTS1R/PXR1 | |
Rabbit | |
Antigen affinity purification | |
RUO | |
5830 | |
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
|
IgG |
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot | |
Unconjugated | |
Immunohistochemistry (1:50-1:200) Western Blot (1:250-1:500) Immunofluorescence (1-4 ug/mL) The optimal working dilution should be determined by the end user. | |
PEX5 | |
PEX5 | |
Recombinant protein corresponding to amino acids of human PEX5. | |
100 μL | |
Primary | |
Human, Mouse | |
Liquid |
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For Research Use Only